How is cord blood used today?

Today, cord blood stems cells are used in the treatment of nearly 80 diseases, including a wide range of cancers, genetic diseases, and blood disorders.2 In a cord blood transplant, stem cells are infused in to a patient’s bloodstream where they go to work healing and repairing damaged cells and tissue. When a transplant is successful, a healthy new immune system has been created. 

Who can use cord blood stem cells in treatment?

There is often confusion over who can use cord blood stem cells in treatment — the baby they were collected from or a sibling? The short answer is both, but it very much depends on the condition being treated. And it's ultimately the treating physician's decision.

Most of the diseases on the proven treatment list are inherited genetic diseases. Typically, these treatments require a donor transplant, as from a sibling. In fact, research shows that treatments using cord blood from a family member are about twice as successful as treatments using cord blood from a non-relative.9a,17 To date, of the 360+ ViaCord families that have used their cord blood 56% were for transplant.1

When you bank your child’s cord blood with ViaCord, your child will have access to stem cells that are a perfect genetic match.  Some cancers like neuroblastoma are autologous treatments. Ongoing regenerative medicine clinical trials are using a child's own stem cells for conditions like autism and cerebral palsy. 104, 109 To date, of the 360+ families that have used their cord blood 44% were for regenerative medicine research.

Used in the treatment of nearly 80 diseases today.

Cord blood stem cells can be used in the treatment nearly 80 diseases today. Click on a category below to see specific diseases. Note: Banking cord blood does not guarantee that treatment will work and only a doctor can determine when it can be used.

CANCERS

  1. Acute lymphoblastic leukemia (ALL)

  2. Acute myeloid leukemia (AML)

  3. Burkitt's lymphoma

  4. Non-Hodgkin's lymphoma

  5. Myelodysplastic syndrome (MDS)

  6. Lymphomatoid granulomatosis

  7. Juvenile myelomonocytic leukemia (JMML)

  8. Hodgkin's lymphoma

  9. Chronic myelomonocytic leukemia (CMML)

  10. Chronic myeloid leukemia (CML)

BONE MARROW FAILURE SYNDROMES

  1. Amegakaryocytic thrombocytopenia

  2. Congenital dyserythropoietic anemia

  3. Congenital sideroblastic anemia

  4. Cyclic neutropenia

  5. Diamond-Blackfan anemia

  6. Dyskeratosis congenita

  7. Evan's syndrome

  8. Fanconi anemia

  9. Glanzmann's disease

  10. Juvenile dermatomyositis

  11. Kostmann's syndrome

  12. Red cell aplasia

  13. Severe aplastic anemia

  14. Shwachman syndrome

  15. Thrombocytopenia with absent radius (TAR syndrome

  16. Autoimmune neutropenia (severe)

BLOOD DISORDERS

  1. E-β+ thalassemia

  2. E-βo thalassemia

  3. HbSC disease

  4. Sickle βo Thalassemia

  5. Sickle-cell anemia (hemoglobin SS)

  6. α-thalassemia major (hydrops fetalis)

  7. β-thalassemia intermedia

  8. β-thalassemia major (Cooley's anemia)

METABOLIC DISORDERS

  1. Adrenoleukodystrophy Gaucher's disease (infantile)

  2. Alpha mannosidosis

  3. Gunther disease

  4. Hermansky-Pudlak syndrome

  5. Hunter syndrome

  6. Hurler syndrome

  7. Hurler-Scheie syndrome

  8. Krabbe disease (globoid cell leukodystrophy)

  9. Lesch-Nyhan disease

  10. Maroteaux-Lamy syndrome

  11. Metachromatic leukodystrophy

  12. Mucolipidosis Type II, III

  13. Niemann Pick Syndrome, type A and B

  14. Sandhoff Syndrome

  15. Sanfilippo syndrome

  16. Tay-Sachs Disease

IMMUNODEFICIENCIES

  1. Adenosine deaminase deficiency

  2. Ataxia telangiectasia

  3. Chronic granulomatous disease

  4. DiGeorge syndrome

  5. IKK gamma deficiency

  6. Immune dysregulation polyendocrineopathy

  7. Leukocyte adhesion deficiency

  8. Myelokathexis X-linked immunodeficiency

  9. Omenn's syndrome

  10. Reticular dysplasia

  11. Severe combined immunodeficiency

  12. Thymic dysplasia

  13. Wiskott-Aldrich syndrome

  14. X-linked agammaglobulinemia

  15. X-linked lymphoproliferative disease

  16. X-linked Mucolipidosis, Type II

OTHER

  1. Hemophagocytic lymphohistiocytosis

  2. Osteopetrosis

  3. Langerhans cell histiocytosis

Regenerative medicine - the therapuetic potential of cord blood continues to grow.

The therapuetic potential of cord blood continues to grow.  Over the last few years cord blood use has expanded into an area known as regenerative medicine. Regenerative medicine is the science of living cells being used to potentially regenerate or facilitate the repair of cells damaged by disease, genetics, injury or simply aging. Research is underway with the hope that cord blood stem cells may prove beneficial in young patients facing life-changing medical conditions once thought untreatable - such as autism and cerebral palsy.