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Treatable Diseases and Future Uses of Umbilical Cord Blood Stem Cells

Today, cord blood stems cells are used in the treatment of nearly 80 life-threatening diseases, including a wide range of cancers, genetic diseases, immune system deficiencies, and blood disorders (see list below).

ViaCord is proud to play a key role in the success of umbilical cord blood transplants that help treat these life-threatening diseases. We are especially proud of the 225 transplants and infusions to date that have used units processed by ViaCord and CHORI, the Childrens' Hospital Oakland Research Institute.

Cancers
 

  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Burkitt's lymphoma
  • Chronic myeloid leukemia (CML)
  • Juvenile myelomonocytic leukemia (JMML)
  • Non-Hodgkin's lymphoma
  • Hodgkin's lymphoma
  • Lymphomatoid granulomatosis
  • Myelodysplastic syndrome (MDS)
  • Chronic myelomonocytic leukemia (CMML)

Bone Marrow Failure Syndromes 
 

  • Amegakaryocytic thrombocytopenia
  • Autoimmune neutropenia (severe)
  • Congenital dyserythropoietic anemia
  • Cyclic neutropenia 
  • Diamond-Blackfan anemia
  • Evan's syndrome
  • Fanconi anemia
  • Glanzmann's disease
  • Juvenile dermatomyositis
  • Kostmann's syndrome
  • Red cell aplasia
  • Schwachman syndrome
  • Severe aplastic anemia
  • Congenital sideroblastic anemia
  • Thrombocytopenia with absent radius (TAR syndrome)
  • Dyskeratosis congenita

Blood Disorders/Hemoglobinopathies
 

  • Sickle-cell anemia (hemoglobin SS)
  • HbSC disease
  • Sickle βo Thalassemia
  • α-thalassemia major (hydrops fetalis)
  • β-thalassemia major (Cooley's anemia)
  • β-thalassemia intermedia
  • E-βo thalassemia
  • E-β+ thalassemia

Metabolic Disorders 
 

  • Adrenoleukodystrophy
  • Gaucher's disease (infantile)
  • Metachromatic leukodystrophy
  • Krabbe disease (globoid cell leukodystrophy)
  • Gunther disease
  • Hermansky-Pudlak syndrome
  • Hurler syndrome 
  • Hurler-Scheie syndrome
  • Hunter syndrome
  • Sanfilippo syndrome
  • Maroteaux-Lamy syndrome
  • Mucolipidosis Type II, III
  • Alpha mannosidosis
  • Niemann Pick Syndrome, type A and B
  • Sandhoff Syndrome
  • Tay-Sachs Disease
  • Batten disease (inherited neuronal ceroid lipofuscinosis)
  • Lesch-Nyhan disease

Immunodeficiencies
 

  • Ataxia telangiectasia
  • Chronic granulomatous disease
  • DiGeorge syndrome
  • IKK gamma deficiency
  • Immune dysregulation polyendocrineopathy X-linked
  • Mucolipidosis, Type II
  • Myelokathexis
  • X-linked immunodeficiency
  • Severe combined immunodeficiency
  • Adenosine deaminase deficiency
  • Wiskott-Aldrich syndrome
  • X-linked agammaglobulinemia
  • X-linked lymphoproliferative disease
  • Omenn's syndrome
  • Reticular dysplasia
  • Thymic dysplasia
  • Leukocyte adhesion deficiency

Other

 

  • Osteopetrosis
  • Langerhans cell histiocytosis
  • Hemophagocytic lymphohistiocytosis

          Emerging Treatments

           

          • Diabetes
          • Cerebral Palsy
          • Brain Injury

          To learn more about potential future uses for cord blood stem cells click here.

           

          Although the potential use of umbilical cord blood is expanding rapidly, the odds that family member without a defined risk will need to use their child's umbilical cord blood are low. There is no guarantee that the umbilical cord blood will be a match for a family member or will provide a cure. Autologous cord blood stem cells will not guarantee suitable treatment for all inherited genetic diseases. As with any transplant therapy, therapeutic success depends upon many factors beyond the stem cells themselves including patient condition, type of disease, recipient-donor relationship and matching, and other factors. The use of cord blood stem cells for emerging treatments is experimental.

           

          Watch inspirational stories of families touched by ViaCord.

            Visit the Gift Registry

           

           

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