The Evolution of Research
Dr. Joanne Kurtzberg at Duke University Medical Center was the first to perform a reinfusion of a child's own cord blood for the treatment of cerebral palsy. Since then, the team at Duke has launched three clinical research studies to understand the potential for this regenerative therapy.
A Phase I clinical research study first demonstrated safety. A Phase II study followed to determine efficacy for children using their own umbilical cord blood for the treatment of spastic cerebral palsy. Study results, presented at the 57th American Society of Hematology Annual Meeting, showed that when patients were give an adequate dose of their own cord blood stem cells, their Gross Motor Function Measure (GMFM-66) improved significantly.111 A third Cerebral Palsy study is now underway to determine safety when using stem cells from the cord blood of a sibling. Further details can be found on clinicaltrials.gov.