Newborn Stem Cells in Research

In 1988, the first child was treated with an allogeneic cord blood unit from a sibling to treat Fanconi’s anemia.77 Since that first successful transplant 25 years ago, cord blood stem cells have been used over 35,000 times in the treatment of nearly 80 diseases.2,4 These diseases include a wide variety of cancers, blood disorders, hemoglobinopathies, bone marrow failure syndromes metabolic disorders and immunodeficiencies.2,47 Click here to review the list of diseases where cord blood stem cells were used in treatment. Stem cell research has contributed greatly to the expanding uses of cord blood. Preclinical and clinical research continues to advance the potential of newborn stem cells, with the goal of treating diseases that currently have no treatment or cure.

Cord Blood Research

Research continues to seek advanced applications for these stem cells, specifically in the areas of regenerative medicine. Regenerative medicine involves replacing or "regenerating" cells to restore normal function. The following diseases and conditions have been the subject of pre-clinical and clinical research:


Type 1 Diabetes 32

Cerebral Palsy 28,29

Autism74

Spinal Cord Injuries75

Stroke68

Heart Disease69

Muscular Dystrophy78

Cord Tissue Research

As medicine advances, we are learning more about the potential benefits of cells derived from umbilical cord tissue. MSCs from cord tissue can readily differentiate into a range of cells, which differ from the cell lineages found in cord blood.48 Cord tissue stem cells are being studied to shed light into their potential medical value. Pre-clinical evidence supports the potential for future treatments in the following areas:


Parkinson's Disease 20

Type 1 Diabetes 23

Sports Injuries 26

Liver Fibrosis 24

Lung Cancer 25

Breast Cancer76

Stroke22

Cardiac Inflammation (perivascular MSCs)70

Connective Tissue Healing (perivascular MSCs)71

Dermal Healing (perivascular MSCs)72